Reason cold/flu/covid vaccines are -40% effective instead of +95% is big-pharma patent technologies monopoly abuse partial vaccination profit-motives and conservative low-knowledge low-intellectual development anti-vaxxers. Mandatory Global Annual Simultaneous Vaccination Eradicates as proven in Nova Serrana, Brazil, where 50% efficacy clinical trial covid inactive virus vaccine was +95% effective with mandatory/compliant simultaneous general vaccination.
Systemic Life Regeneration (SLR): Human Cells can be fixed (in-vivo mRNA/vDNA gene reprogramming to differentiated young cell:Oct4/Sox2/Klf4), replaced (ex-vivo mRNA/vDNA gene reprogramming to undifferentiated/differentiated stem/young cell, tissue, organ: Oct4/Sox2/Klf4 +cMyc for Stem ), destroyed (immune system), divided (DNA telomere extension with hormone/enzyme telomerase), stimulated (cytokine peptide outside cell signaling), nurtured/oxygenated (direct vascular glucose/oxygen and other nutrient supplementation to back healthy cell expansion) to maintain or progress Systemic, Cellular, Atomic, Genetic, Informatic Life levels in Permanent Life Paradigm and Protocol.
vDNA (vector/retroviral/neutral viral shell), can be used to change/instruct DNA that than activates mRNA. vDNA could have higher risks/potential errors, than using directly mRNA for reprogramming, a more scalable, lower cost, more productive, better for clinical/industrial mass production of stem cells or younger cells ex-vivo or supplementation for in-vivo production via a mRNA vaccine/supplement. iPSC, Induced Pluripotent Stem Cell can be produced with pluripotency related genes, Reprogramming/Transcription Factors, as Oct4/Pou5f1, Sox2, Klf4 and cMyc. Reprogramming/Transcription Factors, pluripotency genes, as Oct4, Sox2, Klf4, bring cell to original/young differentiated state, plus cMyc to stem non-differentiated state, in-vivo/ex-vivo for internal/external cell/tissue/organ/body regeneration/biobuilding and bio-cyber doctor-bot Nbot, Neurobot bio-cyber building, dual mitotic bio-cyber independent Artificial Intelligence structure that can be divided for donation to protect/support Live of the original DNA donor, while maintaining/protecting the original/independent/ donator.
IUI can eliminate virus, bacteria, cancer, toxin, trauma, aging; in addition to in-vivo cell telomere extension replication, plus Reprogramming factors/genes regeneration, plus ex-vivo stem cell, tissue, organ and full body (Nbot), can provide full Systemic Permanent Life Protection. If technology not available and/or Systemic Life, cells with natural integration systems, regresses to Cellular Life, supplemented by artificial integration systems, regeneration can be applied while patient in "coma" instead of typical/eventual Life abandonment with 99,99% living cells to be buried or burned. If Cellular Life protection tech not available or general/regional artificial circulation not possible, than Life must be regressed to Atomic/Molecular Life hibernation (flash/dry freezing), deactivating cells for future progression with defrost/dehibernation/regeneration protocols already available.
nDNA, Nuclear DNA can be damaged with time by structural break/gene replacement/mutation that is usually repaired/destroyed and/or activation/deactivation of genes by position of gene strand, that could be rebooted/rejuvenated to original state by reprogramming genes. Telomere ends wear out, if not rebuilt by hormones producing the enzyme Telomerase to extend Telomeres. mt DNA, Mythocondrial DNA, can be damaged by its high oxidation environment. Superoxide Dismutase for example is an enzyme counteracting this damage and can be supplemented to avoid turn for example into dysfunctional Senescence Cell. That can be an alternative to apoptosis/destruction of cell, with a physical/spatial/structural function, or if not they may just consume resources as cancer cells and avoid replacement for healthy cells that could be naturally or artificially supplemented in-vivo/ex-vivo.
ALR, Accelerated Localized Regeneration, 3D bio in/ex-vivo, tumor/trauma/defect immune/structure, cells/cytokines/enzymes/nutrient/RNA/DNA, nano/micro/mini infusion, as via a micro catheter, has lower cost higher performance than traditional macro or micro surgery/chemo/radio interventions, macro being the worst in terms of invasive high risk higher costs lower performance, often directly and indirectly lethal, as infections, hemorrhage, thrombosis or cancer.
IUI, Individual Universal Immunotherapy, accelerates ex-vivo (outside the body) immunity process that occurs naturally in-vivo (inside body), by reducing the space, time and strategy choice. Allows immune system to identify the pathogen threat (antigen), prepare antibodies (obstruct pathogen from entering healthy cells), load attack-ready immune cells with antigen information and load information immune cells to inform other information/attack cells inside body. Identifies, solves obstacles, destroys pathogens, regenerates body, accelerating cure for any disease/trauma/aging caused by any pathogen (virus/bacteria/fungus), dysfunctional cell (cancer, senescent), toxin or trauma, saving time/space with quality/quantity supplementation of natural/proven immunity processes developed over a billion years by trial/error, reducing them, accelerating new solutions if necessary.
ICU (Intensive Care Unit) can be advanced and compacted into a PLM (Permanent Life Module) including an IUI-Machine-product (Individual Universal Immunotherapy Machine) with curative IUI-Ex-Vivo-Service complementing preventive SAV-SAT-SAS-In-Vivo-Product (Super Auto Vaccine/Test/Supplement) for All-Age brackets, 0-25-50-75-100-125-Beyond, covered by Medical-Fund-Insurance-Dividend-Reward, part of the Permanent-Life-Paradigm-Protocol-Product.
Super Auto Supplements, Nutrition (protein/aminoacids, vitamins, glucose, lipids), Enzymes (as telomerase, telomere extension, HTC, Hydride Transfer Complex, protects cell against hypoxia/lack of oxygen), Cytokines (cell signaling against trauma/bacteria/virus/toxin/cancer as chemokines, interferons, interlukins, lymphokines, Tumor necrosis Factors), Hormones, Growth Factors, Trehalose (insect sugar, cryopreservative, protects cell membranes against dehydration, high/low temperature, hypoxia, can be converted to glucose with trehalase and the opposite with glucase).
Super Auto Vaccine, spray/patch/pill/spring, mandatory yearly until eradication, cold/flu/covid, exosome/mosaic with any number of virus nano-particle fragments, strengthens immune system verified by Super Auto Test to receive Medical Dividend. Flu/Cold/Covid pandemic then endemic with +1 million Life abandonment (aka "death") per year because of non mandatory vaccination in endemic regions and use of symptomatic drugs that eliminate 1st line of defense.
Life abandonment, organ harvesting is inefficient/illegal, under 20% transplant efficacy and over 95% Permanent Life Protocol efficacy. Organ/tissue scaffold ECM Extra Cellular Matrix decellularized, recellularized, 3DBioprinted hydrogels, ex/in-vivo with DNA/immune compatible farmed stem cells and IPSC, Induced Pluripotent Stem Cells. ECM mainly composed of macromolecule proteoglycans/fibrous proteins as collagens/elastins/fibronectins/laminins.
When cell membrane channels are covered because of inter-cellular obstruction or space pressure limitation, cell can cease to function, as in sodium/potassium ion exchanges, and so one of the defenses of body is to release the cell into bloodstream to be recycled to other tissues/organs if healthy or to be discarded via kidney/urine if dysfunctional as in cancer. Another defense from cell channel membrane dysfunction would be to eliminate or isolate it to prevent growth. Cancer metastasis, cancer cell leaving an area and joining another, implies a failure of the 3 defense systems to eliminate/isolate it on the spot or to discard it in bloodstream/urine.
Superblood can filter/clean blood from dysfunctional cells, add functional tissue/organ cells, trained antibodies and immune cells ex-vivo, outside body, reintroduce them in-vivo, into body, allowing cancer cells to be eliminated and replaced by healthy cells. If new healthy cells are fed into blood stream from outside body culture, the body mistake of taking unidentified cancer cells as healthy into tissue/organ will decrease and new trained antibodies immune cells will flag cancer cells and avoid incorporation to other tissue destroying them on bloodstream or escorting them out via kidney/urine.
Cells with membrane ion channel obstruction can be released into bloodstream to other tissues/organs if healthy or eliminated by immune blood cells or discarded via kidney if unhealthy. Cancer metastasis is a failure of this process to be fixed by Superblood when eliminating them on the spot or isolating them, as benign nodule, fails because tissue/organ immune cells couldn't identify/eliminate them.
Auto low cost pill, patch, spray, spring injection of nutrient, metabolic, regeneration supplementation, as vitamins, proteins, glucose/trehalose, hormones, enzymes, mRNAs (messenger)/vDNAs (vector/vehicle) for human cell protein production. Gene fixing/perfecting modification with vDNA, vector/vehicle DNA molecule (plasmid, virus, nanobot, nanoparticle, microinjection, electroporation, magnetofection, hydrodynamic injection) used to carry DNA segment to host cell, can produce a permanent internal fixing/perfecting of cell as opposed to external supplementation, as for genetic mutation dysfunctions.
As FLU/COVID, MALARIA vaccine low efficacy 20-40% in line with big pharma profits, because of wrongful delivery only to risk groups and/or non-mandatory and/or non-simultaneous for all starting in epidemic area. VACCINE EFFICACY PROPORTIONAL TO SIMULTANEOUS COVERAGE OF ALL POTENTIAL HOSTS. ZERO HOSTS ERADICATES DISEASE AND ENDS PROFITS.
Multiviral/Mosaic Binding-Receptor-Domain nano particles ex-vivo vaccine eradicates Covid-Flu-Cold with preventive mandatory, annual, simultaneous AutoVac spring-pill-patch-spray delivery and curative SuperVac, ex-vivo antigen/antigen receptor loaded immune cells and antibodies.
Biocyber Neurobot Artificial Bone-Marrow and Thymus-Spleen produces/trains immune cells/antibodies for Superblood/lymph, DNA specific Individual Universal Immunotherapy mini-system cell and antibody bank donor. 3D organ/tissue/cell bio-degradable scaffold/structure bio-printing, Artificial Bone Marrow, Individual Universal Immunotherapy, produce, regenerate. improve immune cells, stromal cells, antibody proteins, to eliminate pathogens and regenerate organs/tissues/cells. Diabetes can be eliminated with life style nutrition/exercise profile change, Insulin B cells can be produced, pancreas can be bio 3D printed and Individual Universal Immunotherapy can end autoimmune dysfunction probably caused by unidentified or wrongfully perceived pathogen. MFSD1 protein can make Individual Universal Immunotherapy more efficient by making cancer targets still and help assembling tissues and organs making cells stick to each other. They stimulate cell membrane integrin receptors to adhere to other cells and also to the in-vivo natural extracellular matrix or ex-vivo artificial scaffold.
Immune cells can be regenerated with hormone/enzyme, as telomerase to increase telomeres and dividing capacity or gene inducing to pluripotent stem cell and back. In addition to new somatic to stem cell to immune cell, with particular antigen training or gene engineering, can raise immune capacity, specially at an advanced age, allowing general hormone/enzyme/telomerase supplementation, reducing/eliminating telomere reduction cellular dysfunction, to neutralize potential environment/genetic cancer or non rejuvenated senescent cells. They can also regenerate and repair damaged organs and tissues in-vivo and/or ex-vivo, since organ/tissue/blood different DNA donations are inefficient/damaging/illegal and must be replaced by same DNA repair/regeneration or full 3D tissue/organ bio or bio-cyber printing.
Partial-vaccination industry profits billions from overpriced vaccines, symptomatic drugs and emergency visits. Vaccination technique requires EVERYBODY vaccinated at the same time from epidemic hot spots to all regions. Partial-vaxxers are as damaging/dangerous as anti-vaxxers and responsible for viral epidemic to pandemic to endemic as flu, cold and now covid. Individual Universal Immunotherapy is a Super Vaccine that exo-accelerates endo-natural immune process for immediate high efficacy. Permanent Life Protocol must be applied when traditional primitive medicine declares cardiac/brain electric failure, aka "death", with 99,999999% living cells.
Super Cells can be produced ex-vivo or in-vivo by genetic engineering and/or bio-chimo infusion on in-vivo cells, gametes, embryos, stems, cloned and/or cultured cells. IVSC In-Vivo Super-Cells can be produced by sending new genes via electric focused devices as nano/micro needles, robots, patches, skins, chips, catheters to become multi-cellular structures, blood vessels, nerves and/or organs, supplementing/changing natural regeneration decline to become permanent.
Supercell can be bio-chemical (natural cellular/genetic improved) and/or cyber-quantic (artificial informatic electronic-photonic-gravitonic matter-energy systems). Immune Super Cell (ISC) are ex-vivo/in-vivo trained/improved immune system cells/proteins using human/foreign genetics, antigens, chemicals, proteins/enzymes, stem cells to eliminate virus, bacteria, cancer/senescent/dysfunctional cells, aging, trauma. ISC can locate and directly or indirectly eliminate/fix/regenerate cells sustaining Permanent Life forever. ISCs cultivated ex-vivo packed with cancer antigen, reinforced by chemical to eliminate cancer defenses, may also carry stem cell and telomerase to stimulate telomere growth and local cell division.
In-vivo/ex-vivo membrane markers can attract/train immune cells/antibodies containing destructive/constructive supplements to specific dysfunctional/functional cells, as bio/chimo/enzymes/RNA to destroy/reactivate/fix dysfunctional/cancer/senescent/old cells. Full and/or partial inactivated bacteria and/or virus can be injected in cancerous cells, ex-vivo and/or in-vivo, to induce ex-vivo and/or in-vivo immune cells/antibodies to attack them at the site and generating immune memory/training/antigen to attack them all over the body and to be reinforced by auto vaccine (in-vivo antigen inducing/training antibodies and immune cells) and/or super vaccine (ex-vivo trained immune cells ant antibodies).
Intradermal micro-needle 3D printed patches can be added to mini-needle intramuscular self applied spring injection or manual injection by others, delivering +10 times more efficacy to immune cell rich skin, combine with point of contagion nasal spray and sublingual pill self-application will reduce cost and increase coverage of vaccination. Self testing for pathogen and antibody level can complement the Autovac kit. +95% vaccination coverage of humans and animals can eradicate virus/pathogens, avoiding higher viral loads and mutations created by unvaccinated.
Covid/Flu virus advanced patient contagion/replication/mutation have a pattern to be of non-vaccinated, symptomatic drug users that end up in crowded emergency/infirmary increasing high viral load, followed by passive invasive respiration and life abandonment (aka “death”). Retail symptomatic drugs remove first line of defense (inflammation, pain, congestion and fever) and can be replaced by pre-sympthomathic low cost $1-2 pharmacy/on-line AutoVac Covid/Flu ex-vivo inactive virus/protein self ampoule spring injection, nasal spray and sub-lingual pill, covering +95% of population has sufficient antibody action at contagion point and body for +95% efficacy and post-symptomatic replaced by SuperVac Individual Universal Immunotherapy to raise antibodies.
Immune Cells, as Macrophages and Microglias (neuron protectors) don't only eliminate virus, bacteria, cancer, old/senescent cells or indirectly participate in cell regeneration, they also have evolved to start repairing cells as neuron/cardiac cells that have less regeneration turnover because of their function. Supplementation of these cells can speed up cell reparation and regeneration of heart/brain/spine, as when heart/brain electric stoppage (aka supposed "death") oxygen decrease damages cells.
Medical Dividend for medical compliance as vaccination, no substance abuse and Permanent Life protocol, G$10/day can include conditional dividend lump-sums of
G$100,000 escrow deposit for medical organizations, doctors, relatives and patients, matched if available by US$100,000 in patient assets, for applying the Permanent Life Protocol or transfering the patient to a Mesistem controlled module, facility, hardware and/or software to preserve life. The dividend can be liberated and split 4 ways as reward when the patients recover their Systemic Life, generating increase of productivity that backs the G$ Globolsa.com currency emission and recovers control total/partial over his current assets.
Super-vaccine Individual Universal Immunotherapy cures by accelerating ex-vivo (outside body) the natural process that occurs in-vivo that may not have the speed, quantity and quality necessary to stop a pathogen. AutoVac, self/auto-vaccine ampoule spring injection, nasal spray and sublingual pill also prevents at point of contagion.
Genes have code for synthesis of RNA or protein. RNAs have functions or create proteins to perform functions. So genes can be inserted into a cell using a vector or the RNA or the protein can be directly inserted as a "vaccine" or "supplement" for regeneration of cells, tissue, organs and functions, as restoring vision for blind with light-sensitive proteins.
Auto vaccine ampoules with a bottom automatic spring injection (with a intramuscular and/or subcutaneous range or angle of insertion), plus a top nasal spray, plus a solid ambient temperature preserving sublingual dissolving polymer-eatable-nutritional (as cellulose/alginates) to mobilize immune system immediately and mainly at point of contagion, at a frequency and coverage (target 100%) that will deliver the efficacy needed.
Heart-lung machine external oxygenation will generate abundance of oxygenation to 99,99% of living cells and regeneration of 0,01% lost, while external electrical continuity will eventually allow heart/brain electric autonomy to be restarted and adjusted w/ Defibrillator stimulus. Higher heat blood oxygenation will give higher white/red cell performance versus potential pathogens in advantage at the lower temperature tissue cells.
Internal higher temperature fever and inflammation is an immune system defense against pathogens that reduces their replicating efficiency and flushes them out of the body. External lower temperature makes immune system raise immune cell quantity supplementation to compensate lower efficiency relative to pathogens. If body not at rest, their is higher vulnerability, but if body at rest, this low temperature hibernation increases efficiency for regeneration/protection, since other cells consuming less resources. At +4 Celsius, oxygen consumption is 90% lower (50% less per 10 Celsius reduction), with external blood oxygenation/circulation, immune cell, hydration, vitamin/minerals/vitamin D, vaccination, glucose/nutrition, hormone/enzyme/protein, muscle/nerves energy electrodes (etc) supplementation, body can be protected and stimulated to regeneration, in case of Systemic Life failure, as a heart/brain electric failure (aka supposed "death" when in fact 99,99% of cells are alive/active).
In case heart/brain electric failure is not compensated externally to maintain oxygen supply to cells, low temperature hibernation can reduce oxygen consumption and protect cells, in addition to Immune cell supplementation. Permanent Life Protocol can be also enhanced by immune cells/molecules genetic/artificially engineered/enhanced to be full or higher functioning at lower temperatures, protecting the body against pathogens with higher relative efficiency at lower temperatures as virus, bacteria or cancer, in case of hibernation protocol to reduce oxygen/nutrients consumption. In case of vascular circulation general deficiency/obstruction, hibernation may be upgraded to full cellular deactivation in lower temperatures with the addition of cryopreservatives as trehalose (converted to/from glucose).
Close to 90% invasive respiration end up in life abandonment (aka death). Bubble/non-invasive (head, mouth, half/full body) respirators are sufficient. 45 angle back down resting, protect lungs from defensive congestion flow, flat belly down helps congested lungs clear.
Accelerated emergency development with open pre-vaccination Phase 3 with no placebos (damaging/illegal), mass distribution innovation as nasal/shot Self-Vaccination and IUI/Super Vaccine for immediate cure. Inactive/vector virus vaccine with S spike protein produced ex-vivo with eggs, as Flu vaccine, is highly effective/safe with 100% vaccination and as nasal spray.
Nervous system non-neuronal glial cells provide support/protection for neurons but don't produce electrical impulses as neurons. Glial cells are part of the immune/regeneration cell system responding directly to brain injury. Glial cells genes increase activity during supposed "death" at supposed end of brain electrical activity, even after hours or days, trying to repair neurons.
IUI can support/accelerate glial cell regeneration/protection activity, instead of life abandonment (aka death) that decelerates it, with gradual depletion of resources as oxygen/glucose, leading to gradual cellular collapse and molecular/atomic dispersion into environment. Oxygen, glucose, electric and glial cell supplementation must protect/regenerate neuron cells from systemic dysfunction and improper life abandonment.
No need/right for euthanasia/suicide because of supposed terminal disease. IUI can protect/regenerate Systemic Life from virus, bacteria, toxin, cancer, aging. Permanent Life Protocol can protect/regenerate Cellular, Atomic/Molecular, Genetic/Informatic Life. So called "autoimmune" diseases usually have "unknown cause" (viral/genetic/cancer etc) that can also be managed by Individual Universal Immunotherapy.
"Autoimmune" disease that attack muscles can be managed with IUI strategies as replacing attacked cells (muscle cells) and/or attacker cells (immune cells) with compatible new stem cells, ex-vivo cultivated muscle/immune cells, including using Bio-Bot (nampt-macrophage) injury site seekers to haul muscle cells, in this case, to muscle injury site or lacking regenerating cells.
Nasal multi-viral nano-particle ex-vivo protein-peptide Self Vaccine could be mass produced at +10 billion units/year, with production sent directly to consumers and pharmacies. It would be a complete change of paradigm combined with IUI/Super Vaccine that would end the high cost/profit viral sympthomatic drugs industry, viral emergency pneumonia industry and the now expensive patented vaccine industry taken by the drug industry.
Specially when common vaccine are not yet available in necessary quantity, testing plus IUI immunotherapy Super Vaccine of contaminated can accelerate cure and immunization: extract blood small sample test than if contaminated, extract large sample and centrifuge to separate white immune cells/molecules to be exposed to virus and/or contaminated cells leading to antigen loaded/ready immune cells/molecules (antibodies), re-inject blood accelerating immune response timing to cure and immunity. Global Health Protocol with Annual Vaccination including MultiViral, blocks epidemics. Tracking, Lockdown, Isolation, Testing, Masking, Pre-Vaccination (open phase 3 no placebo) blocks pandemics.
Immune Cells, as specific Nampt-macrophages, deliver proteins (as NAMPT) to stimulate stem cell division for injury regeneration. They can be supplemented by IUI to accelerate this stimulus or they can be used as a BIO-BOT to carry telomerase (enzyme protein) to increase division capability of local cells increasing their division telomeres (end of DNA) and/or deliver ex-vivo cultured new stem cells to the injury/trauma/aging local accelerating regeneration.
Global Annual Multiviral 100% vaccination with ex-vivo spike protein, inactivated virus, artificial/synthetic (poly) peptides (sub-protein), including with self/easy applying intranasal, direct to consumers, pharmacies, employers can deny all hosts and end viruses.
Schools or any crowded organization should only open with 100% vaccination. High viral load/mutation eventually break immune defenses. 100% Annual Global Multiviral Vaccination can end viruses, but nations w/ slowly/partially vaccinating "risk groups" can keep global spread. 100% population Global Annual Multiviral Vaccination deny hosts for virus contamination, replication, mutation. Higher/mutated viral loads threat vaccinated older "high-risk" and non-vaccinated younger "low risk" groups.
ICU/IUI can protect systemic/cellular lives allowing full regeneration. When vascular circulation is not possible, hibernation of hardware (cells) and software (DNA/memory) protects atomic, genetic, informatic lives until progression. Cellular Agriculture can mass produce animal cells. Cellular Medculture can mass-flex produce human cells with individual DNA for regeneration.
An epidemic turned pandemic vaccine emergency protocol must turn a Phase 3 non-placebo clinical trial in open voluntary to isolated or masked/tested citizens and mandatory to non-isolated non-tested citizens. Industry of viral symptomatic drugs followed by emergency pneumonia treatment propagates wrongful/failed theories of live virus herd immunity, high-risk only vaccination and inevitable viral mutation. Denying all hosts to replicate, mutate, contaminate will end viruses. It is more efficient for vaccination logistics cost/speed and protection of "risk groups" to vaccinate them with family members and/or work colleagues, reducing replication, mutation, contamination viral load around them. Organization should open after vaccination of its interacting members.
Vaccination and Life Preservation is a collective decision. There is no individual right not to vaccinate or preserve life. 100% multiviral vaccination leads to viral/pathogen extinction. IUI accelerates vaccine immunity and cures. Super Vaccine immunizes/cures immediately by concentrating, supplementing, testing, antigen loading immune cells ex-vivo/in-vitro (outside body) before in-vivo vascular (re)injection, against virus, bacteria, cancer, fungus, toxin, trauma, aging. Cellular Agriculture technology can be used for Customized Individual Genetic Human Cellular Medculture for mass/flexible production for Immune, Stem Cell bank for Individual Universal Immunotherapy for vaccines for antigen loaded immune cells.
Mass producing human immune/stem/any cells ex-vivo, at low cost for instant delivery or to form preserved Cell Banks, replaces current medical paradigm for the Permanent Life paradigm, including mainly Individual Universal Immunotherapy to preserve Systemic Life. Animal/plant cell industrial cell production techniques (so called meat/wood lab industry) forming stacked sheets of stacked up cells in gel and/or 3D bio printing in hydrogel will eliminate current high cost, lab human intensive, monopoly/oligopoly/cartel abusive price gauging techniques. IUI can replace/supplement vaccines for immediate accelerated immunity/cure for virus, cancer, bacteria, fungus, toxins, trauma and aging.
After lab, animal, human testing (Phase 1,2), Phase 3 clinical trial with placebos (neutral substance leaving paid/desperate volunteer at risk) is unnecessary, expensive, manipulable, inefficient, damaging, illegal and must be replaced by a Compared Efficacy Open Testing: public unlimited volunteers receive vaccine, immunity compared with other vaccines and non-vaccinated. Vaccines mass producing inactivated/proteins/vectors/RNA pathogen outside body are safer, more efficient, specially if combined with IUI, since antigens may be fast loaded into immune cells outside the body delivering immediate immunity or cure to patients when reinjected into body and/or receiving cell supplementation.
Flu virus has killed 50 million in first pandemic waves in 1900s than another 50 million over 100 years after that because of lucrative industry of lack of full coverage vaccination, use of symptomatic drugs, crowded viral overload emergencies/infirmaries and kinetic lung damaging invasive excessive respirators. Covid-2 virus trials show low/high contrast of efficiency between low/high contamination areas/risk groups. Vaccine efficiency is proportional to coverage, and full coverage can deny hosts for replication/mutation ending epidemics/pandemics.
The best new vaccine technology is to produce proteins ex-vivo (spike protein for coronavirus covid-2), outside body, away from immune cells. In-vivo (inside human cells) may generate either less likely attack on virus producing cells (autoimmunity) or more likely not attacking virus since virus protein production is benign to cell, that will not signal with cytokines/chemokines to immune cells a dysfunction in cell because of viral protein production which the immune cells may or not interpret as originating from benign/malignant harmless/damaging virus (or bacteria/cancer/toxin).
New vaccines with methods to produce whole/partial viral/pathogen proteins ex-vivo (outside the body) from mRNA/Human cell or from Insect cells or from very specific artificial/synthetic protein design production, can generate antibody response higher than traditional methods or in-vivo mRNA, which has medium to long term theoretical autoimmune or benign potential reactions that are empirically untested. Mass producing human or pathogen proteins outside the body is safer and more efficient, specially if combined with IUI, since antigens may be fast loaded into immune cells outside the body, delivering immediate immunity or cure to patients. Ex-vivo human hormone, enzyme, protein production can induce/accelerate cell production ex-vivo and/or in-vivo, including immune cells.
The Human Body has around 100 trillion revolving cells made of around 8 octillion atoms that have been around for billions of years. Human cells can be replaced/regenerated/repaired/enhanced forever if immune IUI/cell enhanced system can efficiently clear/replace dysfunctional senescent/cancer/traumatized cells and eliminate aggressive virus/bacteria/toxin. Mass production of pluri/multi/unipotent cells can be achieved with ex-vivo/body quality control (avoiding cancer growth); genetic DNA/RNA modification or supplementation; telomerase supplementation (regrow telomeres to allow unlimited DNA cells division); cell/mitochondria wall repair; hydrogel scaffolding to replicate body ideal replication environment. Mass produced cells can be reintroduced by blood vascular system, 3D printed as organs/tissues and/or macro/mini/micro/nano surgery/catheter/bots.
IUI Immune cell and pluripotent stem cell supplementation can eliminate/replace all dysfunctional cells (senescent, benign/malignant cancer), complemented if quantity necessary by regrowth hormone, enzyme, protein, RNA, DNA supplementation, to enhance continuity of cell division (mitosis), with dysfunctional cell division needing to be suppressed by immune cell supplementation. Ideal is to scale up immune/cell bank production with pluripotent cell cloning and/or RNA/DNA genetic reprogramming. Immune Super Cells created with gene therapy, using DNA/RNA ex-vivo to edit/add genes to ID/eliminate pathogens, can be tested ex-vivo/outside body before going in-vivo/inside body. IUI accelerates immune response.
Regeneration with ex-vivo/body 3D printing with cell and/or enhanced Super Cell, using printer with hydrogel scaffolding to build organs and tissues implemented by macro/mini/micro surgery/catheter.
Regeneration with in-vivo/body hormone, enzime, protein, RNA/DNA supplementation for continuity of cell replication by division (size of telomeres/telomerase) or pluripotent stem cell production stimulation or supplementation; cell/supercell/stem cell/nanobot metallic marker with magnetic navigation; mini/micro/nano catheter/surgery. Regeneration with biochemical molecule signaling/stimulation for health/strength of mitochondria, nucleus and cell walls.
Ex/In-vivo immune cell supplementation/acceleration to clear dysfunctional cells (senescent, benign cancer or malignant cancer with damaging size/spread, virus/bacteria/toxin continuous contamination), depend also on them being replaced, if not may generate tissue loss ("auto immune disease"). Cell cloning or genetic modified to be pluripotent (transformable in any type of cell when needed) or to be a specific cell, allows scaling cell production, limited by cell division limitation (50-54 times).
Defense and regeneration process participation are main functions of immune system. Aging reduces quantity of stem cells, reducing tissue renewal. Stem cell bank blood replenishing can reactivate tissue renewal. Telomeres/mitochondria renewal with telomerase enzyme (hormone induced or direct mRNA protein production) stimulate cell division of healthy or dysfunctional cells which need to be cleared by immune cells. At dysfunctional or trauma wound site, immune cells clear debris/dysfunction and secrete signaling molecules that induce adequate specific cell proliferation and differentiation programming essential for successful regeneration.
In epidemic/pandemic is best to VACCINATE ALL in area, city, region, country in order of highest to lowest contamination with no inter-travel until all vaccinated in both. VACCINATE ALL IN SELECTED HIGH CONTAMINATION AREA better, since flu virus long term pandemic shows that high risk group selection keeps their exposure to high viral load replication and mutation from low risk non vaccinated hosts. Emergency vaccination with known technology is decision of government, not of private supplier. It should be used based on epidemic control loss (failure to use tracking, lock-down, isolation, testing, masking) to avoid pandemic (99% chance vaccine approval x 99% +1 million life loss if not vaccinated). Virus continuous propagation/mutation happens because of failure to vaccinate EARLY ALL potential hosts (covid inactive/vector virus vaccine should have been deployed April/May of 2020 at end/beginning of phase 2/3 clinical trials).
Global Mandatory Annual Inactive/Vector Multiviral Vaccine can eradicate covid, flu, all virus, denying hosts for replication/mutation/dissemination, bankrupting virus symptomatic drug industry, main cause of virus lung spread to become life threat pneumonia.
Vaccine, Inactive/Vector Virus Vaccine, Inactive/Vector Corona-Virus Vaccine, Inactive/Vector Corona-Virus Covid 1 Vaccine are all known/tested/used technologies. Covid 2 Vaccine was lab tested, animal tested, small/large group human tested since may 2020 and could have saved since then +1 million lives. 10/15 times higher price not-emergency new technology mRNA in-vivo vaccine approved, while known technology inactive/vector vaccines should have been since may 2020 by government request.
Inactive/Vector multi-viral vaccines can be 100% effective if 100% of potential hosts are vaccinated denying viral potential replication/mutation (including wild/farm/domestic animals). mRna-in-vivo vaccines have potential auto-immunity/no-immunity reaction from using own cells to produce viral proteins. IUI can process, concentrate, supplement immune system to accelerate virus/cancer cure/immunity, also allowing hormonal/enzyme supplementation to increase cell telomeres allowing unlimited regeneration and life extension, without risk of cancer. Any new vaccine can immediately be used ex-vivo/body with IUI before re-injecting blood in-vivo with ex-vivo results confirmed. Inactive/vector multi-viral annual vaccination and/or IUI for complete eradication must be MANDATORY. Non-vaccinated/non-IUI host, replicate, mutate, raise viral load in air and re-spread virus.
No long pre-testing and mass production vaccine needed with mobile/direct AI Individual Universal Immunotherapy Machine, installed in a Water Battery AI OmniCar, accelerating cure/immunity for virus, bacteria, toxin, cancer, trauma and aging. Placebo clinical trials are expensive, easy to manipulate, damaging, illegal big-gov financed by big-pharma process. Cheaper, non-damaging, legal, difficult to manipulate is comparing efficiency in receiving against total future recipient population. In the case of a mRNA in-vivo vaccine, 195 contamination cases of which 185 were placebo (neutral vaccine recipients), including 30 severe cases, 1 death (technology originally conceived to be ex-vivo for security was changed to in-vivo to raise profit margin and achieve higher short term immunity, but with higher long term no-immunity/auto-immunity collateral effect risks, still untested). All these human beings should have been vaccinated before with known/tested inactive/vector virus vaccine technology, with efficiency compared with to-be-vaccinated.
Mass-Testing Total Population Coverage Prevention with Walk-In, Pick-Up, Delivery including Mail-in Home-Kit (finger blood drop, saliva etc) will more than pay for itself and allow direct efficient service/product treatments as Individual Universal Immunotherapy for accelerated cure and immunization. IUI Machine preserves Systemic Life, processing, supplementing blood, cell banks, curing/immunizing virus, bacteria, toxins, cancer, trauma and aging, even after cardiac-respiratory/brain electric failure (aka "death"), allowing recovery with general circulation, or if obstructed, segmented. Contrary to common sense artificial circulation can maintain alive cells in separated legs, arms, trunk and head for future reattachment, including nano/micro nerve/capillary/muscle reconnection.
Individual Universal Immunotherapy allows any or multiple vaccines to be immediately tested and accelerated outside body, in centrifuged blood white cell concentrate or cultured cell bank, before returning blood for cure/immunity. Inactive/vector/protein virus inserted ex-vivo/body, in blood centrifuged white cell concentrate, accelerates antigen identity and loading to cure/immunize.
When tracking, lock-down, quarantine at epidemic origin and new regions is breached, turning epidemic into pandemic, it's necessary general isolation with IMMEDIATE testing/masking/vaccination of all non-isolated, with tested/known technology vaccines, as inactive/vector virus vaccines (even at phase 2 or 3 in clinical trials for the specific pathogen).
In a pandemic, it is ALWAYS advantageous for non-isolated citizens, exposed to live replicating and mutating virus, to be exposed to inactive/vector virus vaccine. mRNA in-vivo vaccines need to change back to ex-vivo, producing intra-cellular viral proteins separated, before presenting them to immune cells, using IUI, avoiding risk of developing short/long term auto-immunity (when exposed to higher live viral loads) or no-immunity (when exposed to no or lower live viral loads), since healthy cells may be identified as contaminated or viral protein as benign. Inactive/Vector virus vaccine lower dose higher efficiency during a pandemic as opposed to a higher dose, may occur because of pandemic immune overload with live virus, with the opposite occurring in preventive non-pandemic scenarios.
Life abandonment (aka deaths) from exposure to active covid-19 virus: +1.5 million ; Life abandonment from voluntary exposure to vaccines: Zero. Lives saved if non isolated had/are vaccinated:+1 million. Different vaccine risk profiles need different levels of testing: Inactive virus (low), viral vector (mid) and mRNA (high) vaccines. Inactive virus vaccine is a known, long term tested technology and should be deployed immediately for non-isolated in a viral airborne pandemia as Covid-19. Viral vector vaccines have a mid-level testing track record. New mRNA technology has highest need of testing specially long term (lowest potential cost, not necessarily lowest price, given patent system and institutionalized but illegal monopoly abuse, given damages/anti-trust laws).
Voluntary/mandatory inactive/vector viral vaccines for non-isolated are safer than active virus exposure and even safer with use of IUI. Modified mRNA direct in vivo/body vaccine for cells to produce covid-19 spike protein, to then immediately recognize it as an intruder/threat, has potential problems. Immune system could learn cell/infected or protein/benign. This current delivery system of mRNA vaccines is risky, theoretical flawed, empirically long term untested, unnecessary (there inactive/vector vaccines). Ex-vivo delivery of proteins from cells to re-inject immune cells has same problem. They can be fixed using mRNA to inactive pathogen protein cell harvest ex-vivo/body (outside) to introduce in vivo/body (inside) or even better ex-vivo/in-vitro to blood immune cell concentrate (IUI).
Individual Universal Immunotherapy allows Technician and/or automated Artificial Intelligence to accelerate immune antigen extraction response by concentrating immune cells/molecules against pathogen and other strategies until safe immunity/cure is achieved w/ individual safer results. 1 Million covid + 100 Million flu life abandonment = protocol inefficiency. Vaccines can be roll out in days or weeks starting w/ non-isolated or w/ IUI. Vaccines can be tested, cure and immunize from in vitro (lab) to in vivo (body) with IUI, with lower risk, lower cost, shorter time and higher efficency.
Mainstream medical viral protocols resulted in 1 million Life abandonments for Covid-19, 100 million for Flu since the pandemic of early 20th century. It's necessary mandatory annual global multiviral vaccination (not only so called subjective risk groups that depend on the viral load absorbed), isolation of all infected, block use of symptomatic drugs and use of Individual Universal Immunotherapy: accelerate learning timing and risk exposure reduction of Immune system achieving cure/immunity in vitro/lab to in vivo/body using blood concentrate with immune cells/molecules against virus, bacteria, cancer, toxin, trauma and aging.
Individual Universal Immunotherapy can accelerate immune response to trauma, concentrating platelet at hemorrhage and aging, raising telomerase enzyme for healthy cell regrowth and/or using messenger RNA to express reprogramming factors. Enhancement of speed, strength, area coverage and immune functionality of platelets via a SuperCell and/or NanoBot is crucial to eliminate possibility of general hemorrhage or infection. This would be the main reason for the need to hibernation regression of Systemic/Cellular Life to deactivated cell Atomic/Molecular Life and the need for porous circulation in Permanent Life Protocol. Just like new oil to a motor, new/filtered/supplemented/enhanced healthier blood (cells, molecules and plasma) can have an enhancing performance effect in the whole body system.
Ultra-low cost Global Health Insurance from 1 to 5% of +US$20Trillion Global Exports for all near 8 billion Humans with mobile/home treatment, microscopy/microfluid computerized diagnostics, nutrition management/ supplementation, micro/nano robotic low invasive surgery, Individual Universal Immunotherapy, enzime/hormonal supplementation, physical/mental/electrical activity, defensive cellular hibernation equipment and external/internal temporary/permanent artificial organ replacement. Ambulance/Mobile Clinic with Permanent Life Module with Intensive Care Unit and Individual Universal Immunotherapy.
Individual Universal Immunotherapy (IUI) is an accelerated natural supplementation process to eliminate immediately all disease pathogens. Nutrition, hydration, temperature, rest and ideal posture favor the efficiency of the immune system. Internal vaccines can be complemented by nanoparticle spray/cream external vaccines with viral, bacterial, cancer proteins that can induce the immune system at the site of contagion.
The ideal resting posture is around 20-40 degrees of inclination of the bed or post-hip upper body so that defensive immune fluids can drain pathogens, especially from the airway, instead of puddling and spreading them in a traditional posture horizontal rest (respiratory viruses such as influenza and coronavirus, including covid-19). But if there is initial contamination, generating a small accumulation of defensive fluids in the lung, these can be relieved / drained by expanding/opening the chest through several deep breaths followed by forced coughing. Once the lung is significantly contaminated (pneumonia) the most advantageous posture is to be placed on your stomach to drain defensive fluids out of the lung.
Production of excessive defensive fluids, generating super inflammation/congestion/pain, are usually the result of self-medication with symptomatic anti-pain, anti-inflammatory and anti-congestion drugs (avoiding/postponing ideal conditions for the immune system, such as rest, posture, nutrition, hydration and ideal temperature), aggravating infection and symptoms. This is what usually happens in severe complications of viral infections (such as pneumonia of influenza / covid-19 etc.), especially in pandemics, in addition to the high viral load associated with the traditional protocol of centralizing contaminated, small distance between them, poor/collective ventilation and early intubation (in general to try to protect the medical staff and other patients), when the ideal is only the aid with low cost portable oxygen masks, preferably supplied to the patient's home.
Use of symptomatic drugs (pain/congestion) and high dosages of exposure to pathogens (as in overcrowded emergencies/infirmaries, as in the viral pandemic cases of influenza/covid-19) reduces reaction efficiency of immune system, increasing requirement for supplementation, that may be provided in real time or by previous stock of an Individualized Cell Bank. Mass produced home isolation-bubble-bed-ventilator-monitor and remote assistance should expand individual care, avoiding expensive dangerous collective centralized high exposure to stress/virus/bacteria/fungus in congested hospitals.
Idea of circulating live virus to achieve "herd immunity" is inefficient, damaging and illegal (eugenic genocide), since even number of "deaths" (aka Life abandonment) are predictable and it would be less damaging to circulate immediately untested neutralized virus vaccine. In a pandemic re-circulation can be achieved with vest/mask/washing protection, testing to form a closed uncontaminated group and/or Individual Universal Immunotherapy.
Ideal is the formation of a collective macro and/or home micro individual bank of fluids, DNA, gametes, embryos, tissues and cells, especially stem and immunological cells. Preventive vaccines, drugs and other post symptomatic treatments may not work fast enough for many patients that end up being abandoned for supposed "death" after electric heart/brain dysfunction. Global governments can stock/acquire/distribute to all citizens billions of mass produced low cost Environment Hazard Permanent Vests and Masks, against viral, bacterial, radioactive, chemical, pollutants exposure to generate national security, safe work protocol and social-economic confidence.
Natural therapeutic vaccines (immunotherapy) and stem cell regeneration has the best cost benefit for mass universal disease cure and live extension, including in vitro corrective signaling natural substances and processes to avoid immune evasion of virus, bacteria and cancer, to then trigger immune action, to neutralize pathogen and obtain antigen information to spread to other immune cells in vitro, to then reintroduce cells in body, to spread antigen and immune action further, to finally neutralize pathogen in body.
Stem and Immune cell bank is an universal paradigm for treatment for virus, bacteria, cancer, trauma, aging or any dysfunction in the human body. Cost, timing and bureaucratic barriers are usually used as excuse and promise of future use, but can actually be used now. Preventive vaccines can supply, by natural known public technology, information (virus/ bacteria/ cancer antigen) to immune cells. Therapeutic vaccines can provide immune cells already informed and/or ready to attack. Cell/tissue damage natural regeneration can be supplemented by introducing new stem/tissue cells. Patients can retrieve blood and other fluids for preventive testing, to harvest stem and immune cells, to be replicated and cryopreserved in a bank for immediate economic use, when needed, as adding antigen and nuclear transfers, to eliminate any virus, bacteria, cancer or injury to cells and tissues.
Cultured defensive cells/molecules, in vitro to in vivo, can increase immune efficiency and acceleration adding to the pathogen or vaccine in lab blood extract first, so that the antigen may be identified and spread, then injected into the body. Plasma antidote serum of anti-bodies from horses can increase scale and speed of production of antibodies. Genetically enhanced defensive cells, can overcome natural selection evolution of defensive mutations of pathogens. Regeneration can be improved with better identification and elimination of senescent cells, stimulating and opening space for new healthy cells; as long as growth hormones/enzymes as telomerase, DNA telomere growth enzyme, is also at adequate levels, allowing the endings of DNAs to keep adequate size to avoid error in cell split mitosis/meiosis. Platelets and other repair molecules/proteins/enzymes can be added to improve/accelerate trauma repair.
Abusive monopolist pharmaceutical trust companies want to transform this enhanced natural process into an artificial "patented drug" to then abuse monopoly power (abusive price and corrupting political contributions that affect regulation and non-independent judiciary appointments neutralizing anti-trust laws) to offer unregulated, expensive and low efficiency solutions (total cure leads to unwanted price regulation and lower short term profits). This damaging/illegal strategy can eliminate not only long term profits but the management and/or enterprises.
LOWEST COST AND HIGHEST PERFORMANCE HEALTH DEFENSE SUPPLEMENTATION SYSTEM are Immune Cells of an Individual (same DNA), such as Attack/Inform (antigen presenting) Macrophages (M-cells), T-cells (Helper/Killer), B-cells (Antibodies/Cytokines), Inform only Dendritic Cells (D-cells), repair/regenerate Neutrophils (N-Cells) and/or all that remove/repair senescent/dysfunctional cells against aging, present in extracted blood/fluids from patient, replicated, exo/lab exposed to antigen (virus, bacteria or cancer) in highly advantageous ratios (as opposed to endo/body disadvantageous ratios leading to disease symptoms), then reintroduced in body to create higher advantage.
Any disease (low ratio in body)= Immune cell+Antigen informed immune cell + Antigen attack ready immune cell / pathogen < Cure (higher ratio in vitro/lab then transferred back into body). Corrective natural defense signaling substances/molecules, such as extra/intra cellular immunoglobin (antibodies), nucleotides, caspases, interferons, mRNAs, phosphoethanolamine (involved in cell membrane structuring and inducing immune system caspase signaling at the membrane) and exogenous biological, chemical or mechanic help processes, as simple as piercing the infected/dysfunctional cell or nucleus membrane (to expose pathogen, induce cell alarm, trigger immune cell action and antigen identification), can counter attack the immune evasion natural selection mutations of virus, bacteria and cancer.
Antigen loaded antibodies and other defensive molecules could also be harvested from cured/convalescent patients blood/plasma, although the ideal is to harvest directly from treated patient, unless as a last resort to identify pathogen and load antigens (white cells from donors may present auto immune healthy cell attack collateral effects). Antibodies, other defensive molecules and white cells should be concentrated in vitro first at higher ratio against the pathogen to then be transferred back to body, where there is lower ratio (cell culture and cell banks would improve even more efficiency of treatment). Another strategy is to increase neutralized/disabled pathogen as a real time vaccine.
Another resource is corrective or innovative genetic selection/engineering and bio-cybernetic nanotechnology to create immunological supercells/molecules for information/attack or supercells/molecules that are immune to pathogens. Original/new immunological cells/molecules can also be used to locate, inform and/or destroy pathogens using antigens (as for example PSMA, Prostate Specific Membrane Antigen molecule), chemicals (as phosphoethanolamine) or quantic waves (as photonic PET/CT scans, lasers, ultrasounds etc).
Original/new immune cells/molecules can be loaded/marked (nano-cyber-bio-chymo-radio-thermal) to assist in locating/eliminating the pathogens. These can be preventively detected in the blood by many signs such as from damaged white blood cells, elevated levels of certain proteins/molecules, DNA from pathogens, cfDNA (Cell Free DNA) methylation patterns, mutated genes, platelet RNA profiles etc.
Observed in vitro staged battle, between the pathogen and immune cells, leads them to identify the antigen of the pathogen. Antigen informed immune cells in vitro will seek to inform attack cells in body. Antigen already informed attack cells in vitro, will seek to destroy the pathogen in body. It's about staging a battle in vitro (lab) to win the war in the body. Signaling substances and processes may be also taken in body, specially to known concentrations of pathogen, using mini/micro/nano catheter/surgery/robot.
This is a simple endo/exo natural replicating process, that can be carried out regardless of identifying/isolating the antigen or using foreign cells/substances with high potential known/unknown collateral effects. It simply turns an internal losing situation, to an external winning situation, to then turn the internal situation around by reintroducing reinforcements with no or minimal potential collateral effect. No expensive, specific, long clinical trials, patents, barriers of entry, monopoly abuses are necessary. It accelerates the learning curve of an already over a billion year old naturally developed defense system, now enhanced by low cost, high performance systems.
Stem cells and full Individual multi tissue cell lines can be used to supplement/accelerate natural immune cell processes of regeneration. Cells, tissues and/or organs can introduces by nano/micro/mini catheters/surgery/cyber-bio-bots, to regenerate damage caused by virus, bacteria, cancer, trauma or any body dysfunctional process, allowing unlimited protection and extension of Systemic Life, complemented by process/protocol that can also protect Cellular, Atomic, Genetic and Informatic Life levels in the paradigm/protocol of Permanent Life.
Individual Universal Immunotherapy (IUI) can eliminate virus, bacteria, cancer, toxin, aging and trauma at the lowest cost and highest performance in the healthcare industry. It could be applied for example to the covid-19 coronavirus, immediately using the infected patient's blood. Blood extraction with pathogen, infected cell and white cells. Additional extractions, with centrifuge separating white cells (added to the first extraction), red cells (oxygenated) and plasma (add nutrition/supplements).
Concentration of diversified or specific white cells in the first extraction will generate identification, extraction and replication of the antigen, with/without the aid of additional intracellular substances/molecules and/or exogenous mechanical intervention, such as piercing of the cell and/or nuclear membrane to expose the pathogen to the cells or any strategy that facilitates/accelerates the identification of the pathogen/antigen and spread of information to other white cells. Once the white cells are informed and/or ready to attack the pathogen, they are reintroduced in patient along with oxygenated red cells and nurtured/supplemented plasma.
This continuous process will accelerate the patient's recovery, preventing his progress to a severe condition and eventually will immunize him. It is possible to develop hardware/software that automates this continuous process. The existence of a Bank of Immune Cells a priori for all citizens, facilitates and accelerates this process. Even when a ventilator/lung (and/or heart) is not enough, external oxygenation of red cells (oxygenator or heart-lung machine), more antigenization of white cells, more nutrition/plasma supplementation keeps the patient alive and improving.
Immune and Stem
PERMANENT LIFE TECHNOLOGY
HAI IUI MACHINE - Individual Universal Immunotherapy - Immune and Stem Cell Bank Human Artificial Inteligence Hardware/Software against virus, bacteria, cancer, toxins, trauma, aging:
1-Nanoscoper: identifying intra/extracellular pathogens from blood and body fluid.
2-Centrifuger: separating/concentrating white cells, red cells and plasma.
3-Vaccinater: white cell concentration/culture and antigen extraction/information/addition.
4-Oxygenater: red cell concentration/culture and oxygenation.
5-Nurturer: plasma defensive molecules concentration/culture and nutrition/hormones.
6-Marker: cyber-bio-chimo-quantic markers/signalers to locate/eliminate/build.
7-Replicater: pluri/multi/unipotent cell cloning/genetic reprogramming/regrowth stimulator.
IUI SERVICE - Individual Universal Immunotherapy: cure acceleration/immunization/regeneration, senescent/dysfunctional cells remove/repair, immune cell/antibody/antigen/ vaccine/regeneration/growth protein/enzyme/hormone/telomerase/interleukin7 ex/in-vivo boost, against virus, bacteria, cancer, toxins, trauma, aging.
Accelerate/supplement NATURAL TESTED PROCESS ex-vivo/in-vitro/lab, with VERIFIABLE multi-strategies and re-inject to accelerate body results, boosted by in-vivo vaccines.
1-Extract sequential blood samples to centrifuge and separate immune cells/molecules and concentrate them on first sample with pathogen.
2-Follow on electronic microscope the identification of intra/extracellular pathogen and result to extract/inform/load antigen.
3-New immune cells/molecules to spread/load antigen to inform/attack, re-injecting part, until cure.
4-Specific immune cell/molecule versus pathogen until antigen loading acceleration or success.
5-External biological, chemical or mechanical intervention, as membrane piercing, to induce cell alarm to expose pathogen.
6-Neutralized/disabled pathogen as a real time vaccine and/or antibodies from convalescent/cured patient.
7-Cultured defensive cells/molecules; plasma antidote serum of anti-bodies from horses; genetically enhanced defensive cells.
8-Regeneration enhancing immune cells targeting clearing senescent cells; telomerase, DNA telomere growth enzyme; platelets/neutrophils for trauma repair.
9-Nanoparticle spray/cream external vaccines with viral, bacterial, cancer proteins can induce the immune system at the site of contagion.
10-Cyto-bio-chemokines, cell alarm/signaling, identify pathogen, inform/load antigen and regenerate cells in vitro/lab and/or in vivo/body.
11-mRNA to cell harvest proteins with in-vivo auto vaccine or ex-vivo positive, as enzymes or negative, as pathogens, to introduce to blood/immune cell concentrate.
12-Gene therapy using DNA/RNA ex-vivo to edit/add genes to cells, as immune cells to ID/eliminate pathogens and to produce regenerative RNA/proteins.
13-Pluri/multi/unipotent cell immune/tissue cloning/genetic reprogram/regrowth stimulator to clear/replace senescent/cancer cells.
14-Immune cell Bio-Bots, as specific Nampt-macrophages, to accelerate regeneration, protein inducing local or delivered stem cell division.
15-Autoimmune diseases actual viral/genetic/cancer cause or replace attacked/attacker cells w/ compatible new stem/ex-vivo cultivated cells.
16-Oxygen, glucose, electric, glial cell supplementation to protect/regenerate neuron cells from systemic dysfunction leading to improper life abandonment.
17-White/red cell supplementation/oygenation to lower temperature hibernation in case heart/brain electric failure (aka "death") reducing oxygen consumption need.
18-White/red cells higher blood external heat supplementation/oxygenation and genetic/artificially engineered/enhanced to be higher functioning at lower temperatures.
19-Full and/or partial inactivated bacteria and/or virus injected in cancerous cells, ex-vivo and/or in-vivo, to induce ex-vivo and/or in-vivo immune cells/antibodies.
20-In-vivo/ex-vivo membrane markers can attract/train immune cells/antibodies containing destructive/constructive supplements to specific dysfunctional/functional cells.
21-Immune Super Cells produced ex-vivo or in-vivo by genetic engineering/bio-chimo infusion on in-vivo/ex-vivo cells, gametes, embryos, stems, cloned and/or cultured cells.
22-Immune cells can be regenerated with hormone/enzyme, as telomerase to increase telomeres and dividing capacity or gene inducing to pluripotent stem cell and back.
23-MFSD1 can make cancer targets still, stimulating cell membrane Integrin receptors to adhere to other cells and to extracellular matrix, slowing metastasis spread.
24-Regeneration of immune cells with Induced Pluripotent Stem cells; boosting ex-vivo immune supplementation with in-vivo vaccine and growth proteins as Interleukin 7.
25-Filter blood from dysfunctional cells, add functional tissue/organ cells, trained antibodies/immune cells ex-vivo, reintroduce them in-vivo, eliminating/replacing by healthy.
26-Accelerated Natural Biological Restructured Regeneration, tumor/trauma/defect immune/structure cells/cytokines/enzymes/nutrient/RNA/DNA nano/micro/mini infusion.
SUPERVAC/AUTOVAC/SAV, Super Auto Vaccine: Super Vaccine, Immunizes/cures immediately by concentrating, supplementing, testing, antigen loading immune cells/antibodies ex-vivo/in-vitro (outside body) before in-vivo vascular (re)injection, against virus, bacteria, cancer, fungus, toxin, trauma, aging.
Blood Centrifuge Concentration: White Cell (antigen loading)/Red Cell (oxygenation).
Cell Bank: refrigerated, hibernated, cryo/dry freeze, trehalose cryopreservation.
Cellular Medculture: Customized Individual Genetic Human Cellular Medculture mass/flexible production; Cell based production of vitamins, minerals, lipids, carbohydrates, proteins, enzymes, hormones, vaccines, antigen loaded immune cells/antibodies.
Auto Vaccine, self-applied vaccine system, for pathogens as aero-contaminant, repeat, multiviral, ultra low cost, non-cure, preventive, with delayed immunization. Uses animal cellular Medculture harvesting to produce ex-vivo (in-vitro/lab) viral proteins using RNA/DNA, and/or artificial/synthetic viral (poly) peptides (sub-protein), packed in nano-particles/nano-lipids, to be delivered as a auto-applying spray/cream/drop at the main point of contagion, transmission, replication, in this case nasal/respiratory, as sub-lingual pill, mini-needle spring intramuscular injection and micro-needle 3D print intradermal patch. Can be sold directly on line/delivery to consumers and/or local pharmacies, convenient/grocery stores, ending abusive use of symptomatic drugs that reduce immune defenses, leading to pneumonia/emergency/hospitalization).
Auto vaccines ampoules with a bottom automatic spring injection (with a intramuscular and/or subcutaneous range or angle of insertion), plus a top nasal spray, plus a solid ambient temperature sublingual dissolving preserving polymer-eatable-nutritional (as cellulose/alginates), plus intradermal micro-needle 3D printed patch, to mobilize immune system immediately, including at point of contagion, at a frequency and coverage (target 100%) that will deliver +10 times efficacy for 10 times less production and distribution cost.
Multiviral/Mosaic Binding-Receptor-Domain nano particles ex-vivo vaccine eradicates Covid-Flu-Cold with preventive mandatory, annual, simultaneous AutoVac spring-pill-patch-spray delivery and curative SuperVac, ex-vivo antigen/antigen receptor loaded immune cells and antibodies.
AUTOSUP/SAS, Super Auto Supplements: Auto low cost pill, patch, spray, spring injection of nutrient, metabolic, regeneration supplementation, as vitamins, proteins, glucose/trehalose, hormones, enzymes, mRNAs (messenger)/vDNAs (vector/vehicle) for human cell protein production. Ex-vivo/IUI or in-vivo/SAV supplement. Nutrition (protein/aminoacids, vitamins, glucose, lipids), Enzymes (as telomerase, telomere extension, HTC, Hydride Transfer Complex, protects cell against hypoxia/lack of oxygen), Cytokines (cell signaling against trauma/bacteria/virus/toxin/cancer as chemokines, interferons, interlukins, lymphokines, Tumor necrosis Factors), Hormones, Growth Factors, Trehalose (insect sugar, cryopreservative, protects cell membranes against dehydration, high/low temperature, hypoxia, can be converted to glucose with trehalase and the opposite with glucase).
AUTOTEST/SAT, Super Auto Test: blood/saliva/urine multi microfluid testing, multi auto delivery system directly to consumer, patient, authorities proof for Medical Dividend/Reward.
GENEMOD: Gene fixing/perfecting modification with vDNA, vector/vehicle DNA molecule (plasmid, virus, nanobot, nanoparticle, microinjection, electroporation, magnetofection, hydrodynamic injection) used to carry DNA segment to host cell, can produce a permanent internal fixing/perfecting of cell as opposed to external supplementation, as for genetic mutation dysfunctions.
BIOBOT: Immune Cells, as specific Nampt-macrophages, deliver proteins (as NAMPT) to stimulate stem cell division for injury regeneration. They can be supplemented by IUI to accelerate this stimulus or they can be used as a BIOBOT to carry telomerase (enzyme protein) to increase division capability of local cells increasing their division telomeres (end of DNA) and/or deliver ex-vivo cultured new stem cells to the injury/trauma/aging local accelerating regeneration. Vector Bactobot/Virobot, cell delivery inert virus/bacteria.
OLIFE: Acar/Ocar/Olife cube-sphere with ICU Intensive Care Unit, compacted/advanced into PLM Permanent Life Module, CBM Cell Bank Medculture, IUI Individual Universal Immunotherapy, Life Fluid Incubator, compacted/advanced into Abot Avatarbot, dependent cyber digital medical assistant and Nbot Neurobot independent bio-cyber analogic doctor-bot with dual-structure/organs supporting life of cell-donor.
IUI/SAV/SAT/SAS System: Super Auto Vaccine/Super Auto Test/Super Auto Supplements, spray/pill/patch/spring injection multi vaccine and blood/saliva/urine multi microfluid testing, multi auto delivery system directly to consumer, patient, authorities for immunization, prevention, proof for Medical Dividend/Reward; SAS ex-vivo/IUI or in-vivo/SAV supplement. Individual Universal Immunotherapy, accelerates natural tested immuno response, reducing space/time of process ex-vivo, as re-introducing in-vivo antigen loaded immune cells tested ex-vivo, a process that could take more time/space in-vivo to develop, resulting in a symptomatic disease that could even be fatal, leading to Live abandonment as a result as heart/brain electric failure. SAV/SAT/SAS are preventive/pre-sympthomatic, IUI is post-sympthomatic/curative. Delivery by spray/pill/patch/spring (intramuscular spring auto injection), intramuscular/vase needle injection, nano/micro/mini/macro catheter/surgery/bot.
ALR: Accelerated Localized Regeneration, 3D bio in/ex-vivo, tumor/trauma/defect immune/structure, cells/cytokines/enzymes/nutrient/RNA/DNA, nano/micro/mini infusion, as via a micro catheter, has lower cost higher performance than traditional macro or micro surgery/chemo/radio interventions, macro being the worst in terms of invasive high risk higher costs lower performance, often directly and indirectly lethal, as infections, hemorrhage, thrombosis or cancer.
SLR: Systemic Life Regeneration, Human Cells can be fixed (in-vivo mRNA/vDNA gene reprogramming to differentiated young cell:Oct4/Sox2/Klf4), replaced (ex-vivo mRNA/vDNA gene reprogramming to undifferentiated/differentiated stem/young cell, tissue, organ: Oct4/Sox2/Klf4 +cMyc for Stem ), destroyed (immune system), divided (DNA telomere extension with hormone/enzyme telomerase), stimulated (cytokine peptide outside cell signaling), nurtured/oxygenated (direct vascular glucose/oxygen and other nutrient supplementation to back healthy cell expansion) to maintain or progress Systemic, Cellular, Atomic, Genetic, Informatic Life levels in Permanent Life Paradigm and Protocol.